Subacute necrotizing sialadenitis sans is a selflimiting inflammatory lesion of the minor salivary glands of unknown cause. It is considered by some authors to be a distinct entity 1,2 and by others to be part of the spectrum of necrotizing sialometaplasia ns. Computed tomography scan neck, larynx, necrotizing sialometaplasia, salivary glands. Necrotizing sialometaplasia a diagnostic conundrum. This word search, estomatologia ii taller, was created using the my word search puzzle maker. Necrotizing sialometaplasia of tongue tanu randhawa, ipe varghese, shameena pm, sudha s, resmi g nair department of oral pathology and microbiology, government dental college, calicut 673 008, kerala, india address for correspondence. Its clinical appearance, signs and symptoms very often mimic a carcinomatous lesion, thus creating a diagnostic dilemma for the clinician. Gingivitis ulcero necrosante pdf necrotizing ulcerative gingivitis nug is a typical form of periodontal diseases. This is an uncommon benign disease that typically begins with an ulcerated lesion on the hard palate and surrounding tissues. It appears as an aggressive looking lesion in an adult possibly resembling squamous cell carcinoma and mucoepidermoid carcinoma. Necrotizing sialometaplasia is an important lesion as it can be misdiagnosed as a malignancy. Necrotizing sialometaplasia is a benign, selflimited lesion of both major and minor salivary glands, although more commonly the latter. Necrotising sialometaplasia is a rare, benign and selflimiting inflammatory lesion that commonly involves minor salivary glands.
Necrotizing sialometaplasia ns is a benign selflimiting inflammatory condition which can be found at any site in the body that contains elements of the salivary glands, 1,2 the most common site being the palatal mucosa. This may occur not only in the salivary glands but also in sinusnasal tracts and the respiratory tract. All structured data from the file and property namespaces is available under the creative commons cc0 license. A 38yearold man with bilateral ulcerative painful lesions at the junction of the hard and soft palate was presented. Jenzer james p arnold christopher j smith keith d jackson. Classically, it involves the mucoserous glands of the hard palate. Necrotizing sialometaplasia necrotizing sialometaplasias.
All subsequent reports of necrotizing sialometaplasia stress the. Necrotizing sialometaplasia nsm is a benign selflimiting inflammatory lesion of the salivary glands characterized histopathologically by ischaemic lobular coagulative necrosis of seromucinous glands and, squamous metaplasia of ducts and acini. Presentation of the lesion is that of a deep seated ulcer. Necrotizing sialometaplasia of hard palate a case report. Necrotizing sialometaplasia ns is a rare condition which can be easily confused with malignancy. Necrotizing sialometaplasia ns is an uncommon benign reactive necrotizing inflammatory process involving minor salivary gland that often mimics malignancy both clinically and histopathologically. We report the case of a healthy 26yearold man with a painless swelling in the hard palate near the middle raphe, asymptomatic, well.
Necrotizing sialometaplasia ns is a benign condition that may be found at any site in the body that contains elements of the salivary gland. Necrotizing sialometaplasia is a disease of adults with four o. Necrotizing sialometaplasia uncommon locally destructive inflammatory condition of the salivary glands. Here we report a case of necrotizing sialometaplasia in a female on left side of hard palate mimicking carcinoma. Mri findings of necrotizing sialometaplasia the british. Necrotizing sialometaplasia registered dental hygienist. It is thought to be the result of an ischemic event of the vasculature supplying the salivary gland lobules. The aim is to add to the existing literature on this condition. Pdf necrotizing sialometaplasia ns is a benign, selflimiting inflammatory reaction of salivary gland tissue which may mimic. Its presentation initially parallels mucoepidermoid carcinoma or squamous cell carcinoma, however, ns is a benign, selflimiting inflammatory disease of the mucussecreting minor salivary glands. Tanu randhawa, department of oral pathology and microbiology, government dental college, calicut 673. Sialometaplasia arising in the ectopic salivary gland. This lesion can mimic a malignant neoplasm, as more frequently it manifests as a submucosal swelling or as an ulcer of the palate.
Necrotizing sialometaplasia radiology reference article. Pdf necrotizing sialometaplasia ns is a selflimiting inflammatory disease, that involves salivary glands, more frequently the minor ones. The cause of necrotizing sialometaplasia is not known, but it is usually preceded by trauma. Download fulltext pdf sialometaplasia necrotizante. Necrotizing sialometaplasia ns is a benign, self limiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma both clinically and histologically and can lead to unnecessary surgical approach. Necrotizing sialometaplasia of the hard palate in a. Microscopically, necrotizing sialometaplasia shows marked similarity to. It is thought to be caused by ischemic necrosis death of tissue due to lack of blood supply of minor salivary glands in response to trauma.
The clinical and histopathologic features of necrotizing sialometaplasia often simulate those of malignancies such as squamous cell carcinoma or salivary gland malignancy. Acute necrotizing ulcerative gingivitis, anug, trench mouth, vincents. Benign lymphoepithelial lesion ectopic salivary gland tissue freys syndrome hiv salivary gland disease necrotizing sialometaplasia mucocele ranula pneumoparotitis salivary duct stricture. The clinical and histological similarity between this entity and a malignant lesion implies a risk of unnecessary radical treatment. Necrotizing sialometaplasia of the palate sciencedirect. Necrotizing sialometaplasia is a benign selflimiting lesion of both major and minor salivary glands although more commonly the latter. Register for a free account existing user log in existing user log in. Necrotizing sialometaplasia ns is a benign, ulcerative lesion, usually located towards the back of the hard palate. Necrotizing sialometaplasia of hard palate a case report figure 3. Necrotizing sialometaplasia nsm is an uncommon inflammatory condition that affects salivary glands. Introduction necrotizing sialometaplasia is a rare inflammatory necrotizing reactive.
Regular follow up is necessary till complete remission of the lesion. Typically, it involves the seromucinous glands located at palate, buccal mucosa, tongue, tonsil, nasal cavity, trachea, larynx, maxillary sinus, and retromolar trigone. This relatively rare condition holds diagnostic importance because of its ambiguous clinical and histopathological presentation that can be misdiagnosed clinically as neoplasia. Clinical and microscopic findings show obvious similarity with a malignant neoplasm. Registered users can save articles, searches, and manage email alerts. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. International journal of dental sciences and research 6, no. Necrotizing sialometaplasia nsm is a benign, selfhealing lesion of salivary glands, which represents less than 1% of biopsied oral lesions. In 1973, abrams et al first reported this condition. Home julyaugust 2000 volume 5 issue 4 necrotizing sialometaplasia. Often painless, the condition is selflimiting and should heal in 610 weeks. Necrotizing sialometaplasia is a rare, benign, selflimiting, necrotizing process involving the minor salivary glands, mainly the mucoserous glands of the hard palate. Necrotizing sialometaplasia ns is a benign selflimiting inflammatory disease of mucussecreting glands, mainly involving the minor salivary glands. Reactive, self resolving condition, mostly affecting the palate heals within 6 10 weeks etiology is thought to be reaction to trauma or smoking in the presence of existing tissue ischemia.
Introduction since the introduction of the term necrotizing sialometaplasia ns in 1973 by abrams et al. Necrotising sialometaplasia, recognised by lobular infarction, necrosis, and simultaneous squamous metaplasia of ducts and acini is a well known condition. Necrotizing sialometaplasia is a selflimiting, variably ulcerated, benign. It is locally destructive, with inflammation to an area of tissue resulting in damage and ischemic necrosis. To the best of our knowledge, only 22 cases of sans have been reported, mostly on salivary palatal glands.
Necrotizing sialometaplasia is a benign inflammatory condition of the salivary gland remnants or elements, which is usually selflimiting. Necrotizing sialometaplasia the journal of laryngology. Necrotizing sialometaplasia is a rare, benign inflammatory disease of the minor mucous salivary glands usually caused by glandular ischemia or trauma, that can mimic malignancy, but has a selflimiting character. Epidemiology most patients are more than 40 years of age, with. Necrotising sialometaplasia is a rare, benign inflammatory lesion primarily involving the minor salivary glands of the hard palate. Sialometaplasia definition at, a free online dictionary with pronunciation, synonyms and translation. Necrotizing sialometaplasia nsm is a rare benign, inflammatory disease of both major and minor salivary glands, although more commonly. Disease bioinformatics research of sialometaplasia, necrotizing has been linked to salivary gland diseases, carcinoma, metaplasia, ulcer, malignant squamous cell neoplasm. Physicians should be aware of its clinical and histological traits in order to avoid unnecessary disfiguring surgery. Files are available under licenses specified on their description page. Awareness of the disease is crucial to avoid undue surgical treatment. Surgical management of necrotizing sialometaplasia of palate balaji. Necrotizing sialometaplasia is an uncommon inflammatory condition that affects salivary glands.
Necrotizing sialometaplasia is a rare benign and selflimiting disease, which commonly affects the minor salivary glands. A case of necrotizing sialometaplasia ns is presented in a female patient, who initially presented as a suspected head and neck malignancy. Metachronous necrotizing sialometaplasia larynx gupta s. The aim of this article is to report a case of necrotizing sialometaplasia with longterm followup. In this article, we are presenting a rare case of symptomatic metachronous necrotising sialometaplasia which was treated surgically and followed up regularly till complete recovery. The study of sialometaplasia, necrotizing has been mentioned in research publications which can be found using our bioinformatics tool below. A diagnostic dilemma jayakiran madala, venkateswararao guttikonda, rajani korlepara, sivaranjani yeluri. Necrotizing sialometaplasia occurred in a 46yearold woman. Moreno garcia and others published sialometaplasia. Some predisposing factors such as smoking, use of alcohol, denture wearing, recent surgery, traumatic injuries.
The clinical and histopathological findings of 12 new cases of necrotizing sialometaplasia are described. A case of necrotizing sialometaplasia in a 37yearold man with clinical documentation on the. A case report observed at the university teaching hospital of yaounde. The lesion often presents itself as a deepseated palatal ulcer with.
There are only a few reports of the proliferative type of sialometaplasia. C, bengondo messanga, nokam abena m, ntep ntep d, kenna e, and mendouga mengne c. We report a case of necrotizing sialometaplasia in middle aged women presenting as a nonulcerated swelling. Sialometaplasia, squamous metaplasia of salivary gland lobules, is a benign condition occasionally presenting with lesions clinically simulating malignancy. Necrotizing sialometaplasia ns is a nonneoplastic inflammatory condition of the salivary glands. Necrotising sialometaplasia being an important differential for an apparent carcinoma should be excluded histologically prior. No treatment has been described previously either for. Necrotizing sialometaplasia ns is a benign, selflimiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma, both clinically and histologically, that creates diagnostic dilemma leading to unwarranted aggressive surgery. Necrotizing sialometaplasia, is a benign inflammatory lesion primarily involving the minor salivary glands of the hard palate.